Pre-surgical (neoadjuvant) immune checkpoint blockade has shown promising activity in multiple cancer types, but the molecular mechanisms are not well understood. Here, we characterized early kinetic
Supplemental table 6 for article titled "T-cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals" by Naranbhai and Nathan et al. CD8+ T cell epitopes in the SA
Interleukin 6 (IL-6) is a pleiotropic cytokine with diverse roles in homeostasis, inflammation, and cancer. Here we performed transcriptional profiling of OT-I CD8+ T cells activated in the presence o
B6 mice were immunized with either 2000 cfu of ova expressing Listeria monocytogenes (LM-ova) or 100ug whle ovalbumin adjuvanted with 50ug polyIC + 50ug anti-CD40 (FGK45). 7 days later, tetramer stain
GP66:I-A b+ spleen T cells were sorted from LCMV infected animals either 7 or 21 days after Clone 13 infection, conditions referred to as Early and Late Chronic. In addition, similar populat
