Studies toward Total Synthesis of Divergolides C and D
收藏NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Studies_toward_Total_Synthesis_of_Divergolides_C_and_D/2427487
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资源简介：
A facile synthesis of the western segment of divergolides C and D has been developed. Exploratory studies with two disconnections, i.e., C4–C5 vs C5–C6, for elaboration of the ansa bridge to the sterically demanding hexasubstituted naphthalenic aromatic core using a chiral synthon assembled from d-glucose via a stereoselective Johnson orthoester rearrangement is described. The studies set the stage for the completion of the total synthesis of the biologically important novel ansamycins, divergolides C and D, and their structural congeners.
创建时间：
2016-02-19
