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Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ446 (compound 4f)

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ446 (compound 4f) Descriptor: 4-azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-[2-(phenylsulfonyl)ethyl]-1,8-naphthyridine-3-carboxamide, Chimeric Sso7d and HIV-1 integrase, MAGNESIUM ION, ... Authors: Lyumkis, D, Jozwik, I.K, Passos, D. Deposit date: 2019-07-18 Release date: 2020-02-12 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis for strand-transfer inhibitor binding to HIV intasomes. Science, 367, 2020

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2019-07-18
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