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Tissue-restricted adaptive type-2 immunity is orchestrated by OX40L expression on group 2 innate lymphoid cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE112937
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We investigated the transcriptional profiles of lung ILC2, Th2 and Treg (Gata3+ and -) cells from naïve and IL-33-treated mice. This experiment accompanies our manuscript, where we showed that IL-33-dependent accumulation of adaptive type-2 immune cells (Th2 and Treg) was dependent on OX40L expression by ILC2. Analysis of gene-expression in FACS purified populations from naïve (2 samples per cell-type) and IL-33-treated mice (2 samples per cell-type).
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2019-03-21
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