Genetic Studies in the Hutterites

We conducted genetic studies of disease-associated quantitative phenotypes, including microbiome and gene expression studies, and common diseases, such as asthma and Alzheimer's disease, by genotyping and/or sequencing in the Hutterites, a founder population of European descent. The Hutterites who have participated in our studies live on communal farms in South Dakota and are related to each other through multiple lines of descent in a 3,657-person, 13-generation pedigree with 64 founders. The small number of founding genomes reduces genetic heterogeneity whereas their communal lifestyle ensures that non-genetic factors are remarkably uniform between individuals. Our sample includes >1,600 subjects who have participated in our studies of fertility (since 1982), asthma, cardiovascular disease and other complex phenotypes (since 1993), microbiome studies (since 2011), and/or immune response (since 2012). The variable 'Total number of consented subjects' reflects the count of subjects with individual level phenotype and genotype data in dbGaP.]]>
This genome-wide association study of serum YKL-40 levels was conducted in 632 members of a large Hutterite pedigree, who are participants in genetic studies of complex phenotypes and common diseases. Ascertainment was population-based and included all individuals ages 6 years and older who were available on the days of our visits to South Dakota. The samples were genotyped using the early access and commercial Affymetrix GeneChip 500k mapping arrays at The University of Chicago.This genome-wide association study of plasma Lp(a) levels was conducted in 357 members of a large Hutterite pedigree, who are participants in genetic studies of complex phenotypes and common diseases. Ascertainment was population-based and included all individuals ages 15 years and older who were available on the days of our visits to South Dakota and provided a blood sample after an overnight fast. DNA samples from these individuals were genotyped using the early access and commercial Affymetrix GeneChip 500k mapping arrays at The University of Chicago.We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).We sampled stool from adult Hutterite individuals during two seasons: winter and summer over the course of one year. Bacterial abundance in the gut was determined using 16S rRNA gene sequencing. Normalized, relative bacterial abundances adjusted for age, sex, and colony/date of sampling were used as the phenotype in genome-wide association studies. Bacteria present in at least 75% of individuals in each season were examined (winter, summer, both seasons combined). The total number of bacterial taxa examined are: 116 (winter), 104 (summer), and 102 (seasons combined).This genome-wide association study of the reproductive trait, family size, was conducted in 269 married men who are members of a large Hutterite pedigree that proscribes contraception and has large family sizes and are participants in genetic studies of fertility. Ascertainment was population-based and included Hutterite men with at least one child. The samples were genotyped using one of three Affymetrix SNP arrays: GeneChip GeneChip 500k mapping Array, Genome-Wide Human SNP Array 5.0, or Genome-Wide Human SNP Array 6.0 at The University of Chicago.This genome-wide association study of the reproductive trait, birth rate, was conducted in 269 married men who are members of a large Hutterite pedigree that proscribes contraception and has large family sizes and are participants in genetic studies of fertility. Ascertainment was population-based and included Hutterite men with at least one child. The samples were genotyped using one of three Affymetrix SNP arrays: GeneChip GeneChip 500k mapping Array, Genome-Wide Human SNP Array 5.0, or Genome-Wide Human SNP Array 6.0 at The University of Chicago.This genome-wide association study of lymphocyte count was conducted in 462 members of a large Hutterite pedigree, who are participants in genetic studies of complex phenotypes and common diseases at the University of Chicago. Samples were genotyped using Affymetrix GeneChip Mapping 500K Array Set. Lymphocyte counts were obtained as part of a standard differential blood count. Individuals who reported taking antibiotics at the time were excluded from further study. Lymphocyte counts were natural logarithm-transformed. And age was included as a covariate in our association test.We examined the genome-wide effects of rare in European variants (REVs) on plasma levels of LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), total cholesterol and triglycerides (TG) in 828 Hutterites. We performed studies on 660,239 variants that were rare (MAF<1%) or absent in European populations in the ExAC, the ESP or 1000 genomes databases, and had genotypes called in at least 400 individuals and occurred at frequencies > 1% in the Hutterites.
We are also depositing association results for 5,894,147 variants that are low frequency (MAF>1%) or common (MAF>5%) in the Hutterites and in European databases.
The 1000 Genome data set from dbSNP was used to annotate and display the association results in the dbGaP genome browser. As a result, variants that are private to the Hutterites will not be displayed.
]]>We examined the genome-wide effects of rare in European variants (REVs) on plasma levels of LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), total cholesterol and triglycerides (TG) in 828 Hutterites. We performed studies on 660,239 variants that were rare (MAF<1%) or absent in European populations in the ExAC, the ESP or 1000 genomes databases, and had genotypes called in at least 400 individuals and occurred at frequencies > 1% in the Hutterites.
We are also depositing association results for 5,894,147 variants that are low frequency (MAF>1%) or common (MAF>5%) in the Hutterites and in European databases.
The 1000 Genome data set from dbSNP was used to annotate and display the association results in the dbGaP genome browser. As a result, variants that are private to the Hutterites will not be displayed.
]]>We examined the genome-wide effects of rare in European variants (REVs) on plasma levels of LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), total cholesterol and triglycerides (TG) in 828 Hutterites. We performed studies on 660,239 variants that were rare (MAF<1%) or absent in European populations in the ExAC, the ESP or 1000 genomes databases, and had genotypes called in at least 400 individuals and occurred at frequencies > 1% in the Hutterites.
We are also depositing association results for 5,894,147 variants that are low frequency (MAF>1%) or common (MAF>5%) in the Hutterites and in European databases.
The 1000 Genome data set from dbSNP was used to annotate and display the association results in the dbGaP genome browser. As a result, variants that are private to the Hutterites will not be displayed.
]]>We examined the genome-wide effects of rare in European variants (REVs) on plasma levels of LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), total cholesterol and triglycerides (TG) in 828 Hutterites. We performed studies on 660,239 variants that were rare (MAF<1%) or absent in European populations in the ExAC, the ESP or 1000 genomes databases, and had genotypes called in at least 400 individuals and occurred at frequencies > 1% in the Hutterites.
We are also depositing association results for 5,894,147 variants that are low frequency (MAF>1%) or common (MAF>5%) in the Hutterites and in European databases.
The 1000 Genome data set from dbSNP was used to annotate and display the association results in the dbGaP genome browser. As a result, variants that are private to the Hutterites will not be displayed.
]]>We examined the genome-wide effects of rare in European variants (REVs) on plasma levels of LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), total cholesterol and triglycerides (TG) in 828 Hutterites. We performed studies on 660,239 variants that were rare (MAF<1%) or absent in European populations in the ExAC, the ESP or 1000 genomes databases, and had genotypes called in at least 400 individuals and occurred at frequencies > 1% in the Hutterites.
We are also depositing association results for 5,894,147 variants that are low frequency (MAF>1%) or common (MAF>5%) in the Hutterites and in European databases.
The 1000 Genome data set from dbSNP was used to annotate and display the association results in the dbGaP genome browser. As a result, variants that are private to the Hutterites will not be displayed.
]]>We examined the genome-wide effects of rare in European variants (REVs) on plasma levels of LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), total cholesterol and triglycerides (TG) in 828 Hutterites. We performed studies on 660,239 variants that were rare (MAF<1%) or absent in European populations in the ExAC, the ESP or 1000 genomes databases, and had genotypes called in at least 400 individuals and occurred at frequencies > 1% in the Hutterites.
We are also depositing association results for 5,894,147 variants that are low frequency (MAF>1%) or common (MAF>5%) in the Hutterites and in European databases.
The 1000 Genome data set from dbSNP was used to annotate and display the association results in the dbGaP genome browser. As a result, variants that are private to the Hutterites will not be displayed.
]]>We examined the genome-wide effects of rare in European variants (REVs) on plasma levels of LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), total cholesterol and triglycerides (TG) in 828 Hutterites. We performed studies on 660,239 variants that were rare (MAF<1%) or absent in European populations in the ExAC, the ESP or 1000 genomes databases, and had genotypes called in at least 400 individuals and occurred at frequencies > 1% in the Hutterites.
We are also depositing association results for 5,894,147 variants that are low frequency (MAF>1%) or common (MAF>5%) in the Hutterites and in European databases.
The 1000 Genome data set from dbSNP was used to annotate and display the association results in the dbGaP genome browser. As a result, variants that are private to the Hutterites will not be displayed.
]]>We examined the genome-wide effects of rare in European variants (REVs) on plasma levels of LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), total cholesterol and triglycerides (TG) in 828 Hutterites. We performed studies on 660,239 variants that were rare (MAF<1%) or absent in European populations in the ExAC, the ESP or 1000 genomes databases, and had genotypes called in at least 400 individuals and occurred at frequencies > 1% in the Hutterites.
We are also depositing association results for 5,894,147 variants that are low frequency (MAF>1%) or common (MAF>5%) in the Hutterites and in European databases.
The 1000 Genome data set from dbSNP was used to annotate and display the association results in the dbGaP genome browser. As a result, variants that are private to the Hutterites will not be displayed.
]]>We calculated a bronchial responsiveness index (BRI) from methacholine challenge studies described in Motika et al. (1). The formula described in Burrows et al. (2) was used for the calculation.We perform a genome wide association study to identify variants conferring risk to the development of AD in the Hutterites. The Hutterites (1, 2) are descendants of 64 founders and related to each other through multiple lines of descent in a 13-generation pedigree. The sample size in this analysis is N=31, including 5 cases and 26 controls.Individuals living in the Hutterite colonies that we visited who were age 6 years and older (for some studies 15 years and older) were invited to participate in our studies of complex phenotypes and the gut and nasal microbiome; see descriptions of individual studies for details on study-specific inclusion/exclusion criteria.]]>
Our sample includes >1600 subjects who participated in our genetic studies beginning in 1982. ]]>