Supporting data for “Maternal Rescue of Post-embryonic Neuroblast Migration in C. elegans C-mannosyltransferase Mutants”

The folder contains two files: Dataset 1 is raw data points used to generate figures in my thesis and a dataset containing gene information. Sheet 1 includes measurements of lengths of different C. elegans strains under a range of temperatures as an indication of their dumpy phenotypes. Sheet 2 summarises the neuronal mismigration phenotype in different wild type and mutant strains. Sheets 3-5 details the maternal and paternal effect of a PVM mismigration phenotype across generations in different strains. Sheet 6 measures the maternal effect of dumpiness in <i>dpy-19</i> strains. Sheets 7 and 8 looks at the penetrance and maternal effect related to the migration of other Q neurons, including AQR, PQR, SDQR and SDQL. Sheet 9 further looks at this maternal effect of the same phenotypes in <i>dpy-19</i> in other genes. Sheets 10 and 11 include the quantification of <i>dpy-19</i> smFISH signals found in different strains at different stages. Sheet 12 is a summary of all <i>C. elegans</i> genes that encode for a WXXWXXW motif and their function. Sheet 13 is the quantification of maternal effects observed in <i>dpy-19(-)</i> strains when m⁶A pathways are knocked-down.Dataset 2 is statistical analysis done to generate significance value for several of the figures above. Sheet 1 includes an unpaired t test to compare the penetrance of a PVM mismigration defect in animals derived from wild-type phenotype and defective-phenotype mothers. Sheets 2-5 are one-way ANOVA tests that measure the significance of dumpiness in <i>dpy-19</i> strains when a maternal effect is in action.