HAMAP database of microbial protein families

HAMAP is a system, based on manual protein annotation, that identifies and semi-automatically annotates proteins that are part of well-conserved families or subfamilies: the HAMAP families. HAMAP is based on manually created family rules and is applied to bacterial, archaeal and plastid-encoded proteins.

HAMAP是一款依托人工蛋白质注释的系统，可识别并半自动注释隶属于高度保守家族或亚家族的蛋白质——这类家族即HAMAP家族。该系统基于人工构建的家族规则，可应用于细菌、古菌以及质体编码的蛋白质。

搜集汇总

背景与挑战

背景概述

HAMAP是一个基于手动蛋白质注释的系统，用于识别和半自动注释高度保守的微生物蛋白质家族。它通过手动创建的家族规则和配置文件，对细菌、古菌及质体编码的蛋白质进行分类和注释，并集成到UniProtKB的自动注释流程中。