Tumorigenic role of Musashi-2 in aggressive mantle cell lymphoma
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001006613
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SOX11 is overexpressed in the highly aggressive conventional mantle cell lymphoma (MCL) but rarely in the indolent non-nodal MCL subtype. We performed RNA-seq of SOX11+ and SOX11- MCLs to search for SOX11-regulated genes that contributed to MCL clinical evolution, identifying Musashi-2 (MSI2) stem cell-related gene. By performing RNA-seq upon MSI2 knockdown or inhibition in MCL, we identified MSI2 as a potential target to inhibit drug resistance in aggressive MCLs.EGA study EGAS00001006613
创建时间：
2023-02-27
