The effects of Arabidopsis genome duplication on the chromatin organization and transcriptional regulation

we performed Hi-C to probe the nuclear organization patterns after genome duplication in Arabidopsis, In connection with RNA-Seq data and ChIP-Seq data, we found that the transcription of a group of genes is specifically affected by the chromatin interactions with epigenome dynamics. Overall design: Performed Hi-C on autotetraploid and wide type Arabidopsis; examination of 2 different histone modifications H3K4me3 and H3K27me3 in autotetraploid and wilde type Arabidopsis, and RNA-seq also used to check the transcriptional changes in these two samples.