Supporting data for: "Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells"

In this repository we deposited the docking poses and the target protein CLIC1 for the paper "Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells". The protein was prepared using Schrödinger Maestro, starting from PDB ID 1RK4. The docking grid is centred on the coordinates 42.19304362195121, 9.568038256097557, 34.70669665853657. The file "verduci_et_al.zip" contains: CLICK1.pdb pose_1.pdb # docking score -2.141 pose_2.pdb # docking score -2.139 pose_3.pdb # docking score -1.864 pose_4.pdb # docking score -1.623 pose_5.pdb # docking score -1.446 pose_6.pdb # docking score -1.360 pose_7.pdb # docking score -1.191