Crystal structure of PYK2 complexed with PF-4618433
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Crystal structure of PYK2 complexed with PF-4618433 Descriptor: 1-[5-tert-butyl-2-(4-methylphenyl)-1,2-dihydro-3H-pyrazol-3-ylidene]-3-{3-[(pyridin-3-yloxy)methyl]-1H-pyrazol-5-yl}urea, Protein tyrosine kinase 2 beta Authors: Han, S. Deposit date: 2009-01-26 Release date: 2009-03-31 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural characterization of proline-rich tyrosine kinase 2 (PYK2) reveals a unique (DFG-out) conformation and enables inhibitor design. J.Biol.Chem., 284, 2009
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2009-01-26
