PRISM Repurposing 19Q3 Dataset

The PRISM Repurposing release contains small molecule viability datasets generated using the Broad Repurposing Library and the PRISM multiplexed cell-line viability assay.The primary PRISM Repurposing dataset contains the results of pooled-cell line chemical-perturbation viability screens for 4,518 compounds screened against 578 cell lines.Data processing steps are described in the README file. Further descriptions of methods are available at https://doi.org/10.1101/730119.

PRISM药物再利用发布版数据集包含了采用布罗德药物再利用文库（Broad Repurposing Library）与PRISM多重细胞系活力检测法（PRISM multiplexed cell-line viability assay）生成的小分子细胞活力数据集。核心PRISM药物再利用数据集包含了针对4518种化合物、在578个细胞系上开展的混合细胞系化学扰动活力筛选结果。数据集处理步骤详见README文件。方法的进一步说明可通过https://doi.org/10.1101/730119查阅。