Catalytic Asymmetric Syntheses of Tyrosine Surrogates
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https://figshare.com/articles/dataset/Catalytic_Asymmetric_Syntheses_of_Tyrosine_Surrogates/2901778
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资源简介:
Amino acid esters 5−11 as tyrosine mimics have been synthesized in excellent enantioselectivity (up to 99.6% ee) and in good overall chemical yields. The key step in the sequence was the Burk’s [Rh(COD)(2R,5R)-Et-DuPhos]BF4-catalyzed asymmetric hydrogenation of enamides with a variety of reactive functional groups.
创建时间:
2016-02-27



