WP5342 - Pathophysiological roles of DUX4 in FSHD1 - Homo sapiens
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The transcription factor DUX4 is normally expressed during the 4-cell stage, activating various pathways leading to cleavage. This pathway shows how the abberrant expression of DUX4 in post-embryonic stages leads to several disturbations in skeletal muscle fibers, leading to adverse outcomes such as inflammation and apoptosis.
创建时间：
2025-04-17
