Co-Crystal Structure of MDM2 with Inhibitor Compound 47
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Co-Crystal Structure of MDM2 with Inhibitor Compound 47 Descriptor: 6-{[(2S,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid, E3 ubiquitin-protein ligase Mdm2 Authors: Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. Deposit date: 2014-01-10 Release date: 2014-04-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2006 Å) Cite: Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres. J.Med.Chem., 57, 2014
创建时间：
2014-01-10
