European Chemical Biology Database

The European Chemical Biology Database (ECBD) collects experimental results from biological screening programs performed within the EU-OPENSCREEN platform. There are 3 chemical libraries in ECBD: bioactive, diverse, and academic. The bioactive library contains compounds selected with a strong emphasis on target coverage and selectivity. The diverse library contains compounds with unbiased chemical diversity, designed by five academic computational chemistry groups. In the academic library, compounds are collected from European chemists.

欧洲化学生物学数据库（European Chemical Biology Database，ECBD）收录了欧盟OPENSCREEN（EU-OPENSCREEN）平台开展的生物筛选项目的实验结果。该数据库包含三类化学文库：生物活性文库（bioactive library）、多样化文库（diverse library）以及学术文库（academic library）。生物活性文库（bioactive library）收录的化合物均经过严格筛选，着重关注靶点覆盖范围与选择性。多样化文库（diverse library）包含具有无偏化学多样性的化合物，由五个学术计算化学团队设计研发。学术文库（academic library）的化合物则收集自欧洲化学家。

搜集汇总

背景与挑战

背景概述

European Chemical Biology Database (ECBD)是EU-OPENSCREEN网络的数据中心，遵循FAIR原则以确保数据的可查找性、可访问性、互操作性和可重用性。该数据库包含超过11万个化合物、31个靶点和124个实验，并涵盖生物活性、多样性和学术三个化学库。