Farnesyl to CoQ10 metabolism
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Coenzyme Q (ubiquinone or CoQ) is an essential lipid in electron transport and an important antioxidant. CoQ synthesis derives from the isoprene biosynthetic pathway in human and yeast cells. There is interest in the use of CoQ10 in particular for the treatment of mitochondrial disorders and neurodegenerative diseases [PMID: 17973981].
辅酶Q(泛醌或CoQ)是电子传递过程中的必需脂质,同时也是重要的抗氧化剂。辅酶Q的合成源于人类及酵母细胞中的异戊二烯生物合成途径。特别是CoQ10在治疗线粒体疾病和神经退行性疾病方面的应用引起了广泛关注 [PMID: 17973981]。
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