Target-bound SpCas9 complex with TRAC chimeric RNA-DNA guide
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Target-bound SpCas9 complex with TRAC chimeric RNA-DNA guide Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... Authors: Donohoue, P, Pacesa, M, Lau, E, Vidal, B, Irby, M.J, Nyer, D.B, Rotstein, T, Banh, L, Toh, M.T, Gibson, J, Kohrs, B, Baek, K, Owen, A.L.G, Slorach, E.M, van Overbeek, M, Fuller, C.K, May, A.P, Jinek, M, Cameron, P. Deposit date: 2021-06-22 Release date: 2021-09-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Mol.Cell, 81, 2021
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2021-06-22
