EGFR(T790M/V948R) in complex with a macrocyclic inhibitor
收藏Protein Data Bank Japan2023-10-25 更新2026-03-28 收录
下载链接：
https://pdbj.org/mine/summary/7u98
下载链接
链接失效反馈官方服务：
资源简介：
EGFR(T790M/V948R) in complex with a macrocyclic inhibitor Descriptor: 19-chloro-18-fluoro-22-methoxy-8,9,11,12,14,15-hexahydro-21H-4,6-ethenopyrimido[5,4-m][1,4,7,10,15]benzotetraoxazacycloheptadecine, Epidermal growth factor receptor Authors: Beyett, T.S, Eck, M.J. Deposit date: 2022-03-10 Release date: 2022-11-23 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.42 Å) Cite: Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19. J.Med.Chem., 65, 2022
创建时间：
2022-03-10
