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TCR repertoire profiling reveals HLA-dependent and persistent T-cell expansions in synovial fluid of patients with spondyloarthritis

ChEBI2023-05-31 更新2026-07-12 收录

T细胞受体谱系

强直性脊柱炎免疫

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11498 数据链接链接失效反馈

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资源简介：

TCR repertoire profiling reveals HLA-dependent and persistent T-cell expansions in synovial fluid of patients with spondyloarthritis

应用场景：

创建时间：

2023-05-31

T细胞发育

T细胞受体谱系

we compare the TCR repertoires of MAIT1 and MAIT17 cells from the mouse thymus using 5’ scRNAseq and scTCRseq of MR1:5-OP-RU tetramer positive thymocytes. A thorough analysis of TCR features between M

NIAID Data Ecosystem120

Parallel T-cell cloning and deep sequencing of the transcripts of human MAIT cells reveal stable oligoclonal TCRÃ repertoire

T细胞受体谱系

MAIT细胞免疫研究

Mucosal-associated invariant T (MAIT) cells are abundant in humans and recognize conserved bacterial antigens derived from riboflavin precursors, presented by the non-polymorphic MHC class I-like mole

NIAID Data Ecosystem80

TCR delta repertoire from peripheral blood of infants followed longitudinally for herpesvirus infections.

T细胞受体谱系

先天性巨细胞病毒感染

Gamma-delta T cells are unconventional T cells that help control cytomegalovirus (CMV) infection in adults. Gamma-delta T cells develop early in gestation, and a fetal public T cell receptor (TCR) clo

NIAID Data Ecosystem60

NGS data of T-cell receptor repertoire of naive CD4 and CD8 T-cells in healthy donors

T细胞受体谱系

免疫组库分析

sequence data of 18 healthy donors (TCRbeta repertoire) and 5 healthy donors (TCRalpha repertoire. See Klarenbeek et al. PLOS ONE 2015 (accepted):Somatic variation of T-cell receptor genes strongly as

NIAID Data Ecosystem80

ROR𝛾t directs upregulation of RAG gene expression in DP thymocytes and serves as a multi-faceted regulator of the Tcra repertoire.. ROR𝛾t directs upregulation of RAG gene expression in DP thymocytes and serves as a multi-faceted regulator of the Tcra repertoire.

T细胞发育

T细胞受体谱系

Naik et al. show that RAG gene upregulation in DP Thymocytes is controlled by DPASE, a DP-specific open chromatin region in RAG locus. Reduced RAG expression in DPASE KO mice result delayed and incomp

NIAID Data Ecosystem70

TCR repertoire profiling reveals HLA-dependent and persistent T-cell expansions in synovial fluid of patients with spondyloarthritis

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