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Human Arginase1 Complexed with Bicyclic Inhibitor Compound 12

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6v7e
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资源简介:
Human Arginase1 Complexed with Bicyclic Inhibitor Compound 12 Descriptor: 3-[(5~{S},7~{S},8~{S})-8-azanyl-8-carboxy-1-azaspiro[4.4]nonan-7-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION Authors: Palte, R.L. Deposit date: 2019-12-08 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Med.Chem.Lett., 11, 2020
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2019-12-08
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