Query proteins (measurement vs prediction) PBMC 160K (top 20 proteins)

We leverage 80% of samples from PBMC160k dataset to build a bimodal reference and use remaining 20% with only mRNA count as query. We expect a powerful mapping method can accurately infer missing modality value of query cells. The measured protein expression will be used as ground truth for validation. Concerto follows similar smoothing protocol as in Symphony and achieves consistent prediction result (Top 20 prediction, Pearson r: 0.966-0.998). scatter_plot_gt.h5ad: the ground truth of protein expression for each cell.scatter_plot_pred.h5ad: the prediction of protein expression for each cell.