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The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90

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Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90 Descriptor: (4E,6E,8S,9R,10E,12R,13R,14S,16R)-19-{[2-(dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16,21-pentamethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Authors: Roe, S.M, Prodromou, C. Deposit date: 2012-04-30 Release date: 2013-04-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (3.08 Å) Cite: Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90. Nat Chem, 5, 2013
创建时间:
2012-04-30
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