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Crystal Structure of Human AKT1 with an Allosteric Inhibitor

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal Structure of Human AKT1 with an Allosteric Inhibitor Descriptor: 1-(1-(4-(7-phenyl-1H-imidazo[4,5-g]quinoxalin-6-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, RAC-alpha serine/threonine-protein kinase Authors: Voegtli, W.C, Wu, W.-I, Lord-Ondash, H.A, Dizon, F.P, Vigers, G.P.A, Brandhuber, B.J. Deposit date: 2010-08-03 Release date: 2010-10-13 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of human AKT1 with an allosteric inhibitor reveals a new mode of kinase inhibition. Plos One, 5, 2010
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2010-08-03
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