Crystal Structure of EGFR-T790M/V948R in Complex with Mavelertinib and EAI001
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Crystal Structure of EGFR-T790M/V948R in Complex with Mavelertinib and EAI001 Descriptor: (2R)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl}pyrrolidin-3-yl]propanamide, ... Authors: Niggenaber, J, Mueller, M.P, Rauh, D. Deposit date: 2020-05-25 Release date: 2020-11-11 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Complex Crystal Structures of EGFR with Third-Generation Kinase Inhibitors and Simultaneously Bound Allosteric Ligands. Acs Med.Chem.Lett., 11, 2020
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2020-05-25
