Adult neurogenesis improves spatial information encoding in the mouse hippocampus - RetroAAV-EE

In vivo two-photon imaging dataset for Frechou et al. "Adult neurogenesis improves spatial information encoding in the mouse hippocampus"

This dataset includes data from retro-AAV injected mice that were housed in an enriched environment (EE). 

For each recording we included raw imaging data consisting of:

Individual frames (.tif files) from 3 consecutive 3 min Ca2+ imaging movies (which were concatenated for analysis)

Microscope settings metadata (Experiment.xml)

Mouse location data (Episode001.h5 in SyncData folder) containing rotary encoder and RFID data

Some analyzed data is also included:

Suite2p analysis data (Suite2p folder)

fluorescence.npy contains raw fluorescence data (the F output of Suite2p data extraction). Rows are individual cells and columns are frames (i.e. timepoints) acquired at 15.253 Hz.

positions.npy contains the position of the mouse on the treadmill belt indexed from 0 to 100.

Both NumPy(.npy) files are the output of the Preprocessing.py code, part of the analysis pipeline used for data analysis in the original publication, which can be found at https://github.com/GoncalvesLab/Frechou-et-al-Neurogenesis

All imaged mice in this dataset were male. Refer to the original publication for additional information.