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Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor Descriptor: 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2 Authors: Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. Deposit date: 2007-04-27 Release date: 2007-06-26 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.72 Å) Cite: Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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2007-04-27
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