Urea Activation of Nitrimines: A Mild, Metal-Free Approach to Sterically Hindered Enamines
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Nitrimines have been identified as impressive starting points for the syntheses of otherwise inaccessible, sterically encumbered enamines. The activation of nitrimines with urea catalysts for reaction with a variety of amines enables the formation of highly substituted enamines in high yield. The reactions benefit from mild, metal-free conditions, high functional group tolerance, and straightforward scale up.
创建时间：
2016-02-18
