Bile acid has recently revealed to be a host factor that regulates gut microbiota in rats. Physiologically-relevant concentration of cholic-acid, a representative primary bile acid in human, was fed t
Stearoyl-CoA desaturase 1 (SCD1) catalyzes the rate limiting step in monounsaturated fatty acid synthesis by inserting a double bond at the delta-9 position of long-chain fatty acids. SCD1 converts st