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NCT03343197: Clinical Biomarker Data

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NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs003148.v1.p1
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Patients with IDH1-mutated low-grade glioma were treated with AG-120 (ivosidenib), AG-881 (vorasidenib), or Placebo for 28 days before surgical resection. A portion of the surgical sample was submitted for exome capture-based transcriptome sequencing (Personalis ACE Whole Transcriptome). Following surgery, subjects had the option to continue (or initiate) treatment with AG-120 or AG-881.This dataset comprises next-generation sequencing data from biopsies obtained in the clinical trial: NCT03343197 (Study of AG-120 and AG-881 in Subjects with Low Grade Glioma).]]> Please see the clinicaltrials.gov page for inclusion / exclusion criteria (https://clinicaltrials.gov/ct2/show/NCT03343197).]]> Please see the clinicaltrials.gov page for study history (https://clinicaltrials.gov/ct2/show/NCT03343197).]]>
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2022-12-07
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