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Human osteosarcoma cells respond to sorafenib chemotherapy by downregulation of the tumor progression factors S100A4, CXCR4 and the oncogene FOS

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE53155
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资源简介:
Osteosarcoma is a rare but aggressive bone neoplasm in humans, which is commonly treated with surgery, classical chemotherapy and radiation. Here, we studied the antimetastatic potential of 4 μM of the multikinase inhibitor Sorafenib in a human osteosarcoma cell line using DNA microarray-based gene expression profiling. 3 untreated replicates of human osteosarcoma cells (ATCC CRL-1543™), 3 replicates of human osteosarcoma cells (ATCC CRL-1543™) treated with 4 µM Sorafenib
创建时间:
2016-01-27
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