Beyond Stronger Antibiotics: Smarter Ecosystems for Infection Control

This research dataset summarizes the structural limitations of the antibiotic-centered paradigm in infection control—including antimicrobial resistance, recurrent infections, and microbiome disruption—and organizes an alternative framework based on microbiome ecosystem–based anti-infective strategies. Rather than pursuing ever “stronger” pathogen-killing drugs alone, the dataset shifts the focus toward designing and restoring the environment in which infections emerge, recur, and persist, incorporating host immunity, microbial balance, treatment history, and ecosystem resilience.