Figure S1 - Androgens Contribute to Sex Differences in Myocardial Remodeling under Pressure Overload by a Mechanism Involving TGF-β

Representative echocardiographic recordings. A: Parasternal short-axis M-mode tracings of the left ventricle at the midpapillary level. LVESd: Left ventricular end-systolic dimension; LVEDd: Left ventricular end-diastolic dimension; PWT: posterior wall thickness; IVST: interventricular septum thickness. Four-chamber M-mode tracings showing the mitral annular plane systolic excursion (MAPSE). C: Peak early transmitral flow velocity (E) from pulsed Doppler tracing. D: Peak early myocardial tissue velocity (E′) of tissue Doppler tracing from the posterior wall in the parasternal short-axis view. E: 2D-guided pulsed Doppler recording of the coarctation gradient in a TAC mouse at the aortic arch, immediately distal to the constriction. (DOC)