Here we describe the efficient synthesis of two oligosaccharide moieties of human glycosphingolipids, globotetraose (GalNAcβ1→3Galα1→4Galβ1→4Glc) and isoglobotetraose (GalNAcβ1→3Galα1→3Galβ1→4Glc), wi

PubMed Central30

E coli ndh KO ALE

生物遗传学

代谢工程

The study aims to understand the adaptive plasticity in bacterial electron transport systems.

NIAID Data Ecosystem20

Identification of Absidia orchidis steroid 11β-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone

类固醇生物合成

代谢工程

Purpose: In order to identify genes for 11β-hydroxylase CYP5311B2 and associated redox partners CPR and cytochrome b5 in filamentous fungus Absidia orchidis AS3.65 Methods: Strand-specific RNA-seq lib

NIAID Data Ecosystem50

Table 1_Targeted UDP-glucose ceramide glucosyltransferase stable overexpression induces a metabolic switch improving cell performance at high cell density.xlsx

病毒载体生产工艺优化

代谢工程

BackgroundViral vectors such as adeno-associated viruses (AAVs) and virus-like particles (VLPs) are critical tools in gene therapy, typically produced using transient gene expression (TGE). Intensific

NIAID Data Ecosystem20

Oliveira2020 - Glycerol pathway for 3-hydroxypropionate production from glycerol

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