Classification of vertebrate GnRHR based on phylogenetic and synteny analysis.

The subtype annotations were based on phylogeny and location on gnathostome ancestor gene linkage blocks GAC A0/C1, GAC A4, and GAC A5. The accession numbers for NCBI and ENSEMBL and gene location are given below the names of the receptors. The receptor names according to our previous classification [13] are shown in parentheses. The five new coelacanth GnRHRs follow current subtype annotation. ′, product of 3R; ″, product of a local duplication after 3R.