National Center for Advancing Translational Sciences COVID-19 OpenData Portal

National Center for Advancing Translational Sciences (NCATS) OpenData Portal development aims to share COVID-19-related drug repurposing data and experiments for all approved drugs. The NCATS OpenData COVID-19 portal is a resource designed for rapid and open sharing of SARS-CoV-2 screening data and assay information for the global health community, measuring over 10,000 compound related assays including the NCATS Pharmaceutical Collection of nearly 3,000 approved drugs. This research was supported by the National Center for Advancing Translational Sciences (NCATS) Intramural Research Program of the NIH, aimed to enable researchers with the resources needed to formulate and test hypotheses, prioritize research opportunities, and efficiently search for effective therapies against viral and disease exposures.

美国国家转化科学推进中心（National Center for Advancing Translational Sciences, NCATS）开放数据门户的开发目标，是面向所有已获批药物，共享与新型冠状病毒肺炎（COVID-19）相关的药物重定位数据及实验成果。NCATS COVID-19开放数据门户是为全球卫生界快速、开放共享严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）筛选数据与检测实验信息而打造的专业资源平台，涵盖超10000种化合物相关检测实验，其中包含近3000种已获批药物组成的NCATS药物馆藏。本研究得到美国国立卫生研究院（National Institutes of Health, NIH）下属美国国家转化科学推进中心院内研究项目的资助，旨在为研究人员提供所需资源，以构建并验证研究假设、优先排序研究方向，并高效搜寻针对病毒及疾病暴露的有效治疗方案。

搜集汇总

背景与挑战

背景概述

该数据集是NCATS（国家转化科学促进中心）的开放数据门户，旨在快速共享与COVID-19相关的药物筛选、变体研究和实验协议数据。它包含了超过1万种化合物的筛选结果，生成了近50万个实验数据点，涵盖抗病毒化合物、SARS-CoV-2靶点筛选、变体活性以及临床前和临床研究等多个方面，以支持全球健康社区加速疗法发现。