Zfp352 over expression chip-seq result

Previous study has determined Dux regulates 2CLC trancriptome via binding and activating MERVL,but the mechanism about the change happned during the 2C-exit process are rarely determined.In this study,we try to illustrate how ZFP352 binds genome location to regulate its downstream trancriptome and 2C-exit process.And make some conclusion and hypothesis about ZFP352 co-binding and interact with other trancription factor:Dux,etc to regulate 2C-exit. Overall design: Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for ZFP352 protein of input and Zfp352 over expression samples