Anti-CD25 Treg targeting antibodies sparing IL-2 signaling promote regression of established glioblastoma tumors and innate cell activation.
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https://www.ncbi.nlm.nih.gov/sra/SRP408075
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Treg depletion in mouse GBM using the anti-CD25 antibody, led to tumor regression and improved survival. We performed single cell RNA sequencing on tumor, lymphoid and myeloid samples from treated and untreated samples Overall design: Myeloid, lymphoid and tumor/stroma cells were isolated using fluorescence-activated cell sorting based on the expression of CD45 and CD11b
创建时间：
2025-05-13
