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Organocatalytic Regioselective Concomitant Thiocyanation and Acylation of Oxiranes Using Aroyl Isothiocyanates

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NIAID Data Ecosystem2026-03-10 收录
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A regioselective and concomitant transfer of thiocyanate (−SCN) and aroyl/acyl (−COR) groups from aroyl/acyl isothiocyanates onto oxiranes was achieved, giving thiocyanato benzoates in 100% atom economy. In this biomimetic organocatalytic process, one part (−SCN) of aroyl/acyl isothiocyanates acts as the nucleophile whereas the other half (−COR) serves as an electrophilic partner.

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2017-01-11
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