Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer
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下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP152523
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资源简介:
To study and compare the effect of siRNA-mediated SRF or Nkx2-5 silencing on androgen-responsive genes in LNCaP cells. Overall design: Human LNCaP prostate cancer cells were transfected with siRNA SmartPools targeting SRF or Nkx2-5 or a non-targeting siRNA SmartPool. Forty-two hours after transfection, cells were treated with synthetic androgen R1881 (5nM) or vehicle. Three biological replicates were generated per treatment group. Forty-eight hours later, total RNA was isolated and processed for RNA-Seq analysis.
创建时间:
2023-01-11



