five

Global phospho-proteomics analysis of the effect of CD25 KO in precursor and mature B-cell

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NIAID Data Ecosystem2026-05-10 收录
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https://www.omicsdi.org/dataset/pride/PXD038996
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To assess the effect of CD25 (Il2ra) knockout on signaling in pre-B leukemia, pre-B cells from CD25-floxed mouse bone marrow were grown ex-vivo with IL-7 and transformed with BCR-ABL1, before treatment with 4-OHT to induce CD25 KO. Phosphoproteomics was performed and differential phosphosites analysed in Cre-ERT2 vs ERT2 samples.
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2026-02-23
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