Source data for the publication: A Cell Pre-Wrapping Seeding Technique for Hydrogel-Based Tubular Organ-On-A-Chip

This data set contains the source data of the publication: Nie, J., Lou, S., Pollet, A.M.A.O., van Vegchel, M., Bouten, C.V.C. & den Toonder, J.M.J. (2024). A cell pre-wrapping seeding technique for hydrogel-based tubular organ-on-a-chip. Adv. Sci. 2024, 2400970. https://doi.org/10.1002/advs.202400970. This paper introduces a novel sugar 3D printing + cell seeding technique to create circular cross-sectioned tubular organ-on-chip models. As a proof of concept, a perfusable renal proximal tubule-on-a-chip is demonstrated with a diameter as small as 50 μm, as well as cellular tubular structures with branches and curvature, and a preliminary vascular-renal tubule interaction model. The data are experimentally obtained with methods described in the publication.

本数据集包含下述发表论文的源数据：Nie, J.、Lou, S.、Pollet, A.M.A.O.、van Vegchel, M.、Bouten, C.V.C. 与 den Toonder, J.M.J.（2024年）发表的《用于构建基于水凝胶的管状器官芯片（organ-on-a-chip）的细胞预包裹接种技术》，刊载于《Advanced Science（Adv. Sci.）》2024年卷，文章编号2400970，DOI：https://doi.org/10.1002/advs.202400970。该研究提出了一种全新的糖基3D打印联合细胞接种技术，用于构建截面呈圆形的管状器官芯片模型。作为概念验证，该工作展示了直径最小可达50 μm的可灌注肾近端小管器官芯片，以及带有分支与弯曲结构的细胞管状组织，同时搭建了初步的血管-肾小管交互模型。本数据集的实验数据均依据该论文中所述的实验方法获取。