ATAC-Seq analysis for Nrf2-dependent chromatin accessibility changes in activated CD4+ T-Cell
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https://dataverse.harvard.edu/citation?persistentId=doi:10.7910/DVN/9RT5XD
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资源简介：
ATAC-seq analysis of wild type (WT) and Keap1-KO (K-KKO) CD4+ T-cells demonstrated significant Nrf2-dependent chromatin accessibility changes. Keap1-KO T-cells exhibit increased chromatin accessibility. Our analysis revealed an upregulation of pathways involved in T-cell proliferation and leukocyte development, suggesting that elevated Nrf2 activity promotes a more proliferative and metabolically active T-cell phenotype.
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Harvard Dataverse
创建时间：
2024-10-04
