Lethal and necrotic toxicity from Eswatini snake venoms in a murine model.

The amount of venom that caused lethality in 50% of mice (LD50) following intravenous injection was determined by Probit analyses, and is reported as μg per mouse, with 95% confidence intervals in parentheses. The minimum amount of venom that caused a lesion approximately 5x5 mm in diameter (MND) following intradermal injection is reported as μg per mouse, with mean lesion area in parentheses. Due to signs of systemic envenoming at higher doses of H. haemachatus venom injection, a smaller lesion area is reported. N.D. = not determined. All experiments used groups of 5 animals.