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Gene expression and small RNA biogenesis
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创建时间:
2023-03-01
相关数据集
The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans
Eukaryotic cells regulate 5’ triphosphorylated (ppp) RNAs to promote cellular functions and to prevent recognition by viral RNA sensors. For example, the triphosphatase domain of RNA capping enzymes
NIAID Data Ecosystem90
Transcriptome analysis of Chd8 S62X heterozygote mutant and wild-type mice
Autism spectrum disorders (ASD) are ~4-times more common in males than females, and CHD8 (a chromatin remodeler)-related ASD shows a strong male bias (~5:1), although the underlying mechanism remains
NIAID Data Ecosystem40
Next Generation Sequencing Facilitates Quantitative Analysis of Reverb fl/fl and Reverb fl/fl /MHC+ cardiac Transcriptomes
We use reverb heart specific ko mouse model to exclude the function of reverb in heart We harvest mice at 6 ZTs and snap frozen the hear samples for transcrptomic analysis.
NIAID Data Ecosystem10
Expression data from kidney cortex of control and transgenic sgk1 mice under DOCA/NaCl treatment. Expression data from kidney cortex of control and transgenic sgk1 mice under DOCA/NaCl treatment
Serum and glucocorticoid-induced kinase 1 (SGK1) regulates blood pressure and has been implicated in inflammation and fibrosis. We have tested whether increased SGK1 activity potentiates mineralocorti
NIAID Data Ecosystem70
High-throughput sequencing of Pol IV and RDR2 transcripts, and their DCL3-diced products, generated from an M13mp18 (+) strand DNA template
In plants, the biogenesis of 24 nt and 23 nt small interfering RNAs (siRNAs) requires NUCLEAR RNA POLYMERASE IV (Pol IV), RNA-DEPENDENT RNA POLYMERASE 2 (RDR2) and DICER-LIKE 3 (DCL3). We show that si
NIAID Data Ecosystem30



