Complete listing of genes within each network.

The genes found to be differentially regulated in our experiments and the number of such genes displayed in the “Focus molecules” column have been highlighted in bold print. The score is generated using a p-value calculation and is displayed as the negative log of that p-value. This score indicates the likelihood that the assembly of a set of focus genes in a network could be explained by random chance alone. A score of 2 indicates that there is a 1 in 100 chance that the focus genes are together in a network due to random chance. Therefore, networks with scores of 2 or higher have at least a 99% confidence of not being generated by random chance alone. The data base attributed general cellular functions to each network which are determined by interrogating the Ingenuity Pathway Knowledge base for relationships between the genes in the network and the cellular functions they impact.