DSPG and CSPG translocate to the lysosome for degradation

As part of the natural turnover of GAGs, extracellular KSPGs translocate to the lysosome to be degraded. The translocation process is unsure but could be either endocytosis from outside the cell or autophagy from inside the cell (Winchester 2005).

在GAGs（糖胺聚糖）的自然更新过程中，细胞外KSPGs（脑脊液蛋白聚糖）迁移至溶酶体进行降解。该迁移机制尚不明确，但可能涉及细胞外部的内吞作用或细胞内部的自噬作用（Winchester 2005）。