TBK1 in Complex with Sulfone Analog of Amlexanox
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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TBK1 in Complex with Sulfone Analog of Amlexanox Descriptor: 2-amino-7-(1,1-dioxo-1lambda~6~-thian-4-yl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, Serine/threonine-protein kinase TBK1 Authors: Beyett, T.S, Tesmer, J.J.G. Deposit date: 2018-03-14 Release date: 2018-12-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.354 Å) Cite: Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKK epsilon for the treatment of obesity. Bioorg. Med. Chem., 26, 2018
创建时间：
2018-03-14
