Formal Synthesis of (±)-Aplykurodinone‑1 through a Hetero-Pauson–Khand Cycloaddition Approach
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https://figshare.com/articles/dataset/Formal_Synthesis_of_-Aplykurodinone_1_through_a_Hetero-Pauson_Khand_Cycloaddition_Approach/4669057
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资源简介：
The
tricyclic intermediate 2 has been synthesized
in eight steps from known compound 6 in 20% overall yield.
As such, this constitutes a highly efficient formal synthesis of (±)-aplykurodinone-1.
This synthesis features a unique, one-pot, intramolecular hetero-Pauson-Khand
reaction (h-PKR)/desilylation sequence to expeditiously
construct the tricyclic framework, providing valuable insights for
expanding the scope and boundaries of h-PKR.
创建时间：
2017-02-20
