Cytotoxic evaluation of the hit compounds.

NIAID Data Ecosystem2026-03-09 收录

抗结核药物

细胞毒性评估

数据链接：

https://figshare.com/articles/dataset/Cytotoxic_evaluation_of_the_hit_compounds_/2647612 数据链接链接失效反馈

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Doxorubicin was taken as control. TI stands for therapeutic index calculated by IC50/GI50 value against H37Rv.

创建时间：

2015-12-07

EthR ligand complex

蛋白质-配体复合物结构

抗结核药物

EthR ligand complex Descriptor: 2-[2-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2,3-triazol-1-yl]ethyl]-6-methyl-1~{H}-pyrimidin-4-one, HTH-type transcriptional regulator EthR Authors: Pohl, E, Tatum, N.

Protein Data Bank Japan2024-01-24 更新30

Viability assay of the cells in vivo conditions after exposure to tested triterpenes 1–6.

细胞毒性评估

三萜化合物药效学

Viability assay of the cells in vivo conditions after exposure to tested triterpenes 1–6.

Figshare2019-03-28 更新20

Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol

蛋白质配体复合物解析

抗结核药物

Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol Descriptor: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-

Protein Data Bank Japan2023-10-04 更新10

Minimal inhibitory concentrations (MIC) of the ethyl acetate extract of Trixis angustifolia DC. (TxAcE) and trixanolides (1a and 1a’) against Mycobacterium tuberculosis H37Rv and nontuberculous mycobacteria.

抗结核药物

天然产物抗菌活性

NIAID Data Ecosystem20

The IC 50 of tylophora alkaloids analogs on the growth inhibition of HepG2 and Huh 7 cells.

药物筛选

细胞毒性评估

The IC50 of these compounds are significantly different (p<0.05) from each other in different magnitude (nM vs µM); while compounds with the same magnitude (nM vs nM and µM vs µM) are not significantl

NIAID Data Ecosystem10

Cytotoxic evaluation of the hit compounds.

资源简介：

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